On May 23, 2018, we published revised versions of our Privacy Policy and User Agreements. Please read these updated terms and take some time to understand them. Your use of our services is subject to these revised terms.
Yes, I Agree.

CannabisNewsBreaks – Data and Safety Monitoring Board Recommends Completion of ARCA biopharma, Inc.’s (NASDAQ: ABIO) GENETIC-AF Trial

Company: ARCA biopharma, Inc. (ABIO)
Category: News

ARCA biopharma (NASDAQ: ABIO) this morning said the GENETIC-AF trial Data and Safety Monitoring Board (DSMB) has completed its pre-specified phase 2B interim analysis and has recommended completion of the study with no changes to the trial design. GENETIC-AF is a clinical trial evaluating Gencaro™ as a candidate for the treatment of atrial fibrillation (AF). The Gencaro development program has been granted Fast Track designation by the U.S. Food and Drug Administration (FDA). “The DSMB stated that there were no safety concerns and that the efficacy results met the prespecified criteria for continuing the Phase 2B trial to completion. We are pleased with the execution of the study thus far with major pretrial assumptions reflected in the trial to date, including genotype frequency, AF/AFL event rate and patient screening rates. We believe the DSMB recommendation is encouraging, as the trial is testing for superior efficacy over the active comparator, TOPROL-XL,” Dr. Michael Bristow, ARCA’s president and CEO, stated in the news release. “We are now focused on completing the Phase 2B trial, which we estimate should include approximately 50% more events than were available at the interim analysis. We look forward to sharing the top-line trial results late in the first quarter of next year, and reviewing the findings with the FDA.”

To view the full press release, visit http://nnw.fm/bW5Xl

About ARCA biopharma

ARCA biopharma is dedicated to developing genetically-targeted therapies for cardiovascular diseases through a precision medicine approach to drug development. ARCA’s lead product candidate, GencaroTM (bucindolol hydrochloride), is an investigational, pharmacologically unique beta-blocker and mild vasodilator being developed for the potential treatment of patients with atrial fibrillation and HFrEF, currently in a Phase 2B clinical trial. ARCA has identified common genetic variations that it believes predict individual patient response to Gencaro, giving it the potential to be the first genetically-targeted atrial fibrillation prevention treatment. ARCA has a collaboration with Medtronic, Inc. for support of the GENETIC-AF trial. The Gencaro development program has been granted Fast Track designation by the FDA. For more information, please visit www.ARCABio.com.

More from CannabisNewsBreaks

SeeThruEquity Issues Update, New PT on IEG Holdings Corp. (IEGH)

Lexaria Bioscience Corp. (CSE: LXX) (OTCQB: LXRP) CEO Discusses Company’s Progress in Interview

IPO Complete, China Internet Nationwide Financial Services, Inc. (NASDAQ: CIFS) Focuses on Providing Financial Solutions to Target Market in China

About CannabisNewsWire

CannabisNewsWire (CNW) is an information service that provides (1) access to our news aggregation and syndication servers, (2) CannabisNewsBreaks that summarize corporate news and information, (3) enhanced press release services, (4) social media distribution and optimization services, and (5) a full array of corporate communication solutions. As a multifaceted financial news and content distribution company with an extensive team of contributing journalists and writers, CNW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. CNW has an ever-growing distribution network of more than 5,000 key syndication outlets across the country. By cutting through the overload of information in today’s market, CNW brings its clients unparalleled visibility, recognition and brand awareness. CNW is where news, content and information converge.

For more information please visit https://www.CannabisNewsWire.com

Please see full terms of use and disclaimers on the CannabisNewsWire website applicable to all content provided by CNW, wherever published or re-published: http://CNW.fm/Disclaimer

CannabisNewsWire (CNW)
Denver, CO
303.498.7722 Office

Official NewsWire Relationships

Benzinga Cannabis Capital Conference Cannabis Business Summit & Expo 2019 Cannabis Drinks Expo MjMicro Conference New England Cannabis Network O'Cannabiz Conference & Expo

Contact us: 303.498.7722